Fetuin A Protein (AA 119-367) (His tag)

Produktnummer ABIN1096642

Recombinant Fetuin A-Protein exprimiert in Human Cells.

Kurzübersicht für Fetuin A Protein (AA 119-367) (His tag) (ABIN1096642)

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 119-367

Aufreinigungstag / Konjugat: Dieses Fetuin A Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Fetuin-A/AHSG/α-2-HS-Glycoprotein/AHSG (C-6His)

Sequenz: APHGPGLIYR QPNCDDPETE EAALVAIDYI NQNLPWGYKH TLNQIDEVKV WPQQPSGELF EIEIDTLETT CHVLDPTPVA RCSVRQLKEH AVEGDCDFQL LKLDGKFSVV YAKCDSSPDS AEDVRKVCQD CPLLAPLNDT RVVHAAKAAL AAFNAQNNGS NFQLEEISRA QLVPLPPSTY VEFTVSGTDC VAKEATEAAK CNLLAEKQYG FCKATLSEKL GGAEVAVTCT VFQTQPVTSQ PQPEGANEAV PTPVVDPDAP PSPPLGAPGL PPAGSPPDSH VLLAAPPGHQ LHRAHYDLRH TFMGVVSLGS PSGEVSHPRK TRTVVQPSVG AAAGPVVPPC PGRIRHFKVV DHHHHHH

Produktmerkmale: Recombinant Human alpha-2-HS-Glycoprotein/AHSG produced by transfected human cells is a secreted protein with sequence (Ala119-Val367) of Human AHSG fused with a polyhistidine tag at the C-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Andere Bezeichnung: fetuin-a

Sub Type: Fusionprotein

Hintergrund: Alpha-2-HS Glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.
Alternative Names: Alpha-2-HS-Glycoprotein, Alpha-2-Z-Globulin, Ba-Alpha-2-Glycoprotein, Fetuin-A, AHSG, FETUA

Molekulargewicht: 38.36 kDa

UniProt: P02765