FBP1 Protein (AA 2-338) (His tag)

Produktnummer ABIN1096624

Produktdetails

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-338

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FBP1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Fructose-1,6-Bisphosphatase 1/FBPase 1 (E. coli, C-6His)

Sequenz: ADQAPFDTDV NTLTRFVMEE GRKARGTGEL TQLLNSLCTA VKAISSAVRK AGIAHLYGIA GSTNVTGDQV KKLDVLSNDL VMNMLKSSFA TCVLVSEEDK HAIIVEPEKR GKYVVCFDPL DGSSNIDCLV SVGTIFGIYR KKSTDEPSEK DALQPGRNLV AAGYALYGSA TMLVLAMDCG VNCFMLDPAI GEFILVDKDV KIKKKGKIYS LNEGYARDFD PAVTEYIQRK KFPPDNSAPY GARYVGSMVA DVHRTLVYGG IFLYPANKKS PNGKLRLLYE CNPMAYVMEK AGGMATTGKE AVLDVIPTDI HQRAPVILGS PDDVLEFLKV YEKHSAQVEH HHHHH

Produktmerkmale: Recombinant Human Fructose-1,6-Bisphosphatase 1/FBPase 1 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala2-Gln338) of Human FBPase 1.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, 1 mM DTT, 1 mM EDTA, 20 % Glycerol, pH 8.0.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Andere Bezeichnung: Fructose-1,6-Bisphosphatase 1/FBPase 1 (FBP1 Produkte)

Hintergrund: Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
Alternative Names: Fructose-1,6-Bisphosphatase 1, FBPase 1, D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP

Molekulargewicht: 37.89 kDa

UniProt: P09467

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport