CFHR1 Protein (AA 19-330) (His tag)

Produktnummer ABIN1096424

Produktdetails

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-330

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CFHR1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Complement Factor H-Related 1/CFHR1 (C-6His)

Sequenz: EATFCDFPKI NHGILYDEEK YKPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCTEEGWS PTPKCLRLCF FPFVENGHSE SSGQTHLEGD TVQIICNTGY RLQNNENNIS CVERGWSTPP KCRSTDTSCV NPPTVQNAHI LSRQMSKYPS GERVRYECRS PYEMFGDEEV MCLNGNWTEP PQCKDSTGKC GPPPPIDNGD ITSFPLSVYA PASSVEYQCQ NLYQLEGNKR ITCRNGQWSE PPKCLHPCVI SREIMENYNI ALRWTAKQKL YLRTGESAEF VCKRGYRLSS RSHTLRTTCW DGKLEYPTCA KRVDHHHHHH

Produktmerkmale: Recombinant Human Complement Factor H-Related 1/CFHR1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Glu19-Arg330) of Human CFHR1 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Andere Bezeichnung: cfhr1 (CFHR1 Produkte)

Sub Type: Fusionprotein

Hintergrund: Complement Factor H-Related 1 (CFHR1) is a 43 kDa secreted member of the factor H family of glycoproteins. The human Complement Factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1 (FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids in length. It contains five, approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation, lipid metabolism and lipoprotein complexes that bind PMNs to LPS.
Alternative Names: Complement Factor H-Related Protein 1, FHR-1, H Factor-Like Protein 1, H-Factor-Like 1, H36, CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2

Molekulargewicht: 36.78 kDa

UniProt: Q03591