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CCL1 Protein (AA 24-96)

Dieses Recombinant CCL1-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN1096254

Kurzübersicht für CCL1 Protein (AA 24-96) (ABIN1096254)

Target

Alle CCL1 Proteine anzeigen
CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Protein-Typ

Recombinant

Spezies

  • 11
  • 5
  • 1
  • 1
Human

Quelle

  • 9
  • 5
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Proteineigenschaft

    AA 24-96

    Verwendungszweck

    Recombinant Human C-C Motif Chemokine 1/CCL1

    Sequenz

    MKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK

    Produktmerkmale

    Recombinant Human C-C Motif Chemokine 1/CCL1 is produced with our E. coli expression system. The target protein is expressed with sequence (K24-K96) of Human CCL1.

    Sterilität

    0.2 μm filtered

    Endotoxin-Niveau

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

    Handhabung

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Lagerung

    4 °C/-20 °C/-80 °C

    Informationen zur Lagerung

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Haltbarkeit

    3 months
  • Target

    CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

    Andere Bezeichnung

    ccl1

    Hintergrund

    Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection.
    Alternative Names: C-C Motif Chemokine 1, Small-Inducible Cytokine A1, T Lymphocyte-Secreted Protein I-309, CCL1, SCYA1

    Molekulargewicht

    8.62 kDa

    UniProt

    P22362
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