DEFB4A Protein (AA 24-64)

Produktnummer ABIN1096116

Dieses Recombinant DEFB4A-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für DEFB4A Protein (AA 24-64) (ABIN1096116)

Target: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 24-64

Verwendungszweck: Recombinant Human β-Defensin 4A

Sequenz: GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P

Produktmerkmale: Recombinant Human beta-Defensin 4A is produced with our E. coli expression system. The target protein is expressed with sequence (Gly24-Pro64) of Human beta-Defensin 4A.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Andere Bezeichnung: beta-Defensin-4A

Hintergrund: Beta-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 beta-Defensins, which are distinguished from alpha-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. beta-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.
Alternative Names: Beta-Defensin 4A, Beta-Defensin 2, BD-2, hBD-2, Defensin, Beta 2, Skin-Antimicrobial Peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B

Molekulargewicht: 4.33 kDa

UniProt: O15263