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ANG Protein (AA 25-147)

Dieses Recombinant ANG-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN1096005

Kurzübersicht für ANG Protein (AA 25-147) (ABIN1096005)

Target

Alle ANG Proteine anzeigen
ANG (Angiogenin (ANG))

Protein-Typ

Recombinant

Spezies

  • 9
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 17
  • 13
  • 2
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Proteineigenschaft

    AA 25-147

    Verwendungszweck

    Recombinant Human Angiogenin/ANG/RNASE5

    Sequenz

    MQDNSRYTHF LTQHYDAKPQ GRDDRYCESI MRRRGLTSPC KDINTFIHGN KRSIKAICEN KNGNPHRENL RISKSSFQVT TCKLHGGSPW PPCQYRATAG FRNVVVACEN GLPVHLDQSI FRRP

    Produktmerkmale

    Recombinant Human Angiogenin is produced by our E. coli expression system. The target protein is expressed with sequence (Gln25-Pro147) of Human Angiogenin.

    Sterilität

    0.2 μm filtered

    Endotoxin-Niveau

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

    Handhabung

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Lagerung

    4 °C/-20 °C/-80 °C

    Informationen zur Lagerung

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Haltbarkeit

    3 months
  • Target

    ANG (Angiogenin (ANG))

    Andere Bezeichnung

    angiogenin

    Hintergrund

    Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin is associated with susceptibility to amyotrophic lateral sclerosis, which is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord.
    Alternative Names: Angiogenin, Ribonuclease 5, RNase 5, ANG, RNASE5

    Molekulargewicht

    14.27 kDa

    UniProt

    P03950
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