Streptolysin O Protein (SLO) (full length)

Produktnummer ABIN1045131

Produktdetails

Target: Streptolysin O (SLO)

Protein-Typ: Native

Proteineigenschaft: full length

Spezies: Streptococcus pyogenes

Quelle: Bacteria

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Purified from Streptococcus hemolyticus

Reinheit: > 95 % (SDS-PAGE)

Anwendungsinformationen

Kommentare:

Full length native Streptolysin O

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Repeated freezing and thawing is not recommended.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 ° C or -80 ° C.

Antigendetails

Target: Streptolysin O (SLO)

Andere Bezeichnung: Streptolysin O (SLO Produkte)

Synonyme: streptolysin O Protein, Streptolysin O Protein, Thiol-activated cytolysin Protein, slo Protein, M6_Spy0188 Protein

Hintergrund: Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.