Lactoferrin Protein (full length)

Produktnummer ABIN1045125

Dieses Native Lactoferrin-Protein wird in Human exprimiert.

Kurzübersicht für Lactoferrin Protein (full length) (ABIN1045125)

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Protein-Typ: Native

Spezies: Human

Quelle: Human

Applikation: Western Blotting (WB), ELISA

Reinheit: > 95 %(SDS-PAGE)

Produktdetails

Proteineigenschaft: full length

Aufreinigung: Purified from human milk

Anwendungsinformationen

Kommentare:

Full length native Human lactoferrin

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Tris pH8.0

Lagerung: -20 °C

Antigendetails

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Andere Bezeichnung: lactoferrin

Hintergrund: Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.

Pathways: Transition Metal Ion Homeostasis