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CSE1L Antigen Profile
Beschreibung des Gens
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.
Alternative names and synonyms associated with CSE1L
CAS/CSE1 segregation protein (Cas) ELISA Kit
chromosome segregation 1 like (CSE1L) ELISA Kit
exportin-2 (LOC100542094) ELISA Kit
chromosome segregation 1 like (cse1l) ELISA Kit
chromosome segregation 1-like (S. cerevisiae) (Cse1l) ELISA Kit