PREX2 Proteine
(DEP Domain Containing 2 (DEPDC2))
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase (By similarity).
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DEPDC2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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Aliase für PREX2 Proteine
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 (PREX2) Proteinephosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2) Proteine
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DEPDC2 Proteine
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P-REX2 Proteine
P-Rex2 Proteine
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