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Presenilin 1 Proteine

(Presenilin 1 (PSEN1))
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1\; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined. [provided by RefSeq, Aug 2008].

8 Treffer

PSEN1 Spezies: Human Wirt: Wheat germ Recombinant WB, AP, AA, ELISA
Produktnummer ABIN1316518
 
PSEN1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, PC, Imm
Produktnummer ABIN7414045
 
PSEN1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, PC, Imm
Produktnummer ABIN7412977
 
PSEN1 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, PC, Imm
Produktnummer ABIN7396037
 
PSEN1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2729570
 
PSEN1 Spezies: Human, Cat, Rind (Kuh), Affe, Schwein Wirt: Escherichia coli (E. coli) Recombinant WB, PC
Produktnummer ABIN2751149
 
PSEN1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant WB, SDS
Produktnummer ABIN6382191
 
PSEN1 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant WB, SDS
Produktnummer ABIN6382195
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Positive Control (PC)
    • Immunogen (Imm)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • ELISA
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Cat
    • Cow
    • Monkey
    • Pig
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 280-379
    • Transcript Variant 1
  • Konjugat
    • His tag
    • Unkonjugiert
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Hersteller
    • antibodies-online
    • Abbexa
    • FabGennix
    • OriGene

Aliase für Presenilin 1 Proteine

presenilin 1 (psen1) Proteine
presenilin 1 (PSEN1) Proteine
presenilin 1 (Psen1) Proteine
presenilin 1 L homeolog (psen1.L) Proteine
ad3 Proteine
AD3 Proteine
Ad3h Proteine
fad Proteine
FAD Proteine
pre1 Proteine
PS-1 Proteine
ps1 Proteine
PS1 Proteine
psen Proteine
s182 Proteine
S182 Proteine
X-PS-alpha Proteine
X-PS-beta Proteine
zf-PS1 Proteine
zfPS1 Proteine
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