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Premelanosome Protein Proteine

(Premelanosome Protein (PMEL))
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011].

8 Treffer

PMEL Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
Produktnummer ABIN1320014
 
PMEL Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN6964099
 
PMEL Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA
Produktnummer ABIN7578887
 
PMEL Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
Produktnummer ABIN7393823
 
PMEL Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5710360
 
PMEL Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
Produktnummer ABIN5713832
 
PMEL Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2725809
 
PMEL Spezies: Human Recombinant
Produktnummer ABIN1065487
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
  • Reaktivität
    • Human
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • Bindungsspezifität
    • AA 25-467
    • AA 1-661
    • AA 25-595
    • AA 470-661
  • Konjugat
    • His tag
    • Fc Tag
    • GST tag
    • His-SUMO Tag
    • Myc-DYKDDDDK Tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Hersteller
    • antibodies-online
    • Signalway
    • ITSI-Biosciences
    • OriGene

Aktuelle Publikationen für unsere Premelanosome Protein Proteine

Rochin, Hurbain, Serneels, Fort, Watt, Leblanc, Marks, De Strooper, Raposo, van Niel: "BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 26, pp. 10658-63, (2013) (PubMed).

Aliase für Premelanosome Protein Proteine

premelanosome protein (PMEL) Proteine
premelanosome protein (Pmel) Proteine
premelanosome protein b (pmelb) Proteine
premelanosome protein a (pmela) Proteine
cb397 Proteine
D10H12S53E Proteine
D12S53E Proteine
D12S53Eh Proteine
fdv Proteine
gp87 Proteine
gp100 Proteine
ME20 Proteine
ME20-M Proteine
ME20M Proteine
MMP115 Proteine
P1 Proteine
P100 Proteine
PMEL17 Proteine
Pmel17 Proteine
pmel17 Proteine
RPE1 Proteine
sb:cb397 Proteine
SI Proteine
Si Proteine
SIL Proteine
SILV Proteine
Silv Proteine
silva Proteine
silver Proteine
silverb Proteine
wu:fc11g11 Proteine
wu:fj24g11 Proteine
zgc:136622 Proteine
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