PRDM16 Produkte
(PR Domain Containing 16 (PRDM16))
Kategorien
The reciprocal translocation t(1\;3)(p36\;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Ausgewählte PRDM16 Kategorien
PRDM16 Antikörper
High quality antibodies with extensive validation data.
PRDM16 ELISA Kits
Reliable ELISA kits for a wide range of species.
PRDM16 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PRDM16 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN6242535
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7164089
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA, ChIP, FACS
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN184809
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PRDM16 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6974822
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958701
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PRDM16 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3094786
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3130708
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Saccharomyces cerevisiae
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5710996
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PRDM16 Produkten
: "PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer." in: Frontiers in cell and developmental biology, Vol. 9, pp. 723777, (2021) (PubMed).: "Binding Efficacy and Thermogenic Efficiency of Pungent and Nonpungent Analogs of Capsaicin." in: Molecules (Basel, Switzerland), Vol. 23, Issue 12, (2018) (PubMed).
: "Capsaicin induces browning of white adipose tissue and counters obesity by activating TRPV1 channel-dependent mechanisms." in: British journal of pharmacology, Vol. 173, Issue 15, pp. 2369-89, (2016) (PubMed).
: "Brown adipose tissue regulates glucose homeostasis and insulin sensitivity." in: The Journal of clinical investigation, Vol. 123, Issue 1, pp. 215-23, (2013) (PubMed).
: "Molecular characterization of a t(1;3)(p36;q21) in a patient with MDS. MEL1 is widely expressed in normal tissues, including bone marrow, and it is not overexpressed in the t(1;3) cells." in: Oncogene, Vol. 23, Issue 1, pp. 311-6, (2004) (PubMed).
: "Breakpoints at 1p36.3 in three MDS/AML(M4) patients with t(1;3)(p36;q21) occur in the first intron and in the 5' region of MEL1." in: Genes, chromosomes & cancer, Vol. 36, Issue 3, pp. 313-6, (2003) (PubMed).
: "A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation." in: Blood, Vol. 102, Issue 9, pp. 3323-32, (2003) (PubMed).
: "A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells." in: Blood, Vol. 96, Issue 9, pp. 3209-14, (2000) (PubMed).
Synonyme und alternative Namen zu PRDM16
PR/SET domain 16 (PRDM16), PR domain containing 16 (prdm16), PR domain containing 16 (Prdm16), PR/SET domain 16 (Prdm16), 5730557K01Rik, C130091E20, csp1, MEL1, mel1, mKIAA1675, PFM13, PRDM16, wu:fc09g08Bezeichner auf Proteinebene für PRDM16
- PR domain containing 16
- fc09g08
- PR domain zinc finger protein 16-like
- MDS1/EVI1-like gene 1
- PR domain zinc finger protein 16
- transcription factor MEL1
- PR domain-containing protein 16
- line 27
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