POT1 Proteine
(Protection of Telomeres 1 (POT1))
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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POT1
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
POT1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
2 Referenzen
POT1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
POT1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
custom-made
POT1
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
POT1
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Aktuelle Publikationen für unsere POT1 Proteine
: "An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity." in: PLoS ONE, Vol. 11, Issue 5, pp. e0156378, (2016) (PubMed).: "The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs." in: Biochimie, Vol. 115, pp. 17-27, (2015) (PubMed).
Aliase für POT1 Proteine
protection of telomeres 1 (POT1) Proteineprotection of telomeres 1 L homeolog (pot1.L) Proteine
protection of telomeres 1A (Pot1a) Proteine
protection of telomeres 1 (Pot1) Proteine
1500031H18Rik Proteine
AI851169 Proteine
DKFZp469P1825 Proteine
HPOT1 Proteine
POT1 Proteine
pot1 Proteine
Pot1 Proteine
Pot1a Proteine
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