anti-Transportin 1 (TNPO1) Antikörper

Bezeichnung:: anti-Transportin 1 Antikörper (TNPO1)

Auf www.antikoerper-online.de finden Sie aktuell 109 Transportin 1 (TNPO1) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Transportin 1 Kits (28) und Transportin 1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 148 Transportin 1 Produkte verfügbar.

Synonyme:: ATTRN1, AU021749, D13Ertd688e, DKFZp469O204, F12A24.13, F12A24_13, IPO2, Kpnb2, MIP, MIP1, TNPO1, transportin 1, TRN

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	TNPO1	3842	Q92973
	TNPO1	238799	Q8BFY9
	TNPO1	309126
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Verknüpfte Pathways mit anti-Transportin 1 Antikörper

CXCR4-mediated Signaling Events

Weitere Produktkategorien zu Transportin 1 Antikörper

Am meisten referenzierte anti-Transportin 1 Antikörper

Mouse (Murine) Monoclonal Transportin 1 Primary Antibody für ICC, FACS - ABIN108620 : Siomi, Eder, Kataoka, Wan, Liu, Dreyfuss: Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins. in The Journal of cell biology 1997 (PubMed)
Show all 7 Pubmed References
Mouse (Murine) Monoclonal Transportin 1 Primary Antibody für ICC, FACS - ABIN108619 : Yu, Boyce, Wands, Bond, Bertozzi, Kohler: Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
Show all 7 Pubmed References
Cow (Bovine) Monoclonal Transportin 1 Primary Antibody für CyTOF, FACS - ABIN269569 : Kawamura, Tomozoe, Akagi, Kamei, Ochiai, Yamada: Identification of the nucleocytoplasmic shuttling sequence of heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its interaction with mRNA. in The Journal of biological chemistry 2002 (PubMed)
Show all 5 Pubmed References

Weitere Antikörper gegen Transportin 1 Interaktionspartner

Human Transportin 1 (TNPO1) Interaktionspartner

TNPO1-mediated nuclear import may constitute a novel input pathway of how cellular redox state signals to the clock, since redox stress increases binding of TNPO1 to PER1 (zeige PER1 Antikörper) and decreases its nuclear localization. TNPO1 is one of the novel players essential for normal circadian periods and potentially for redox regulation of the clock.
A molecular docking and dynamics study concluded that R521C and R521H mutations in FUS (zeige FUS Antikörper) result in weak binding with Karyopherin-beta2 leading to amyotrophic lateral sclerosis.
Data suggest that micoRNA-128 targets the 3prime-untranslated region of nuclear import factor transportin 1 (TNPO1) mRNA.
the TNPO1-Rab8 (zeige RAB8A Antikörper)-ciliary targeting signals complex mediates selective entry into and retention of cargos within cilia.
Together, these results indicate that transportin-1 mediates YB-1 (zeige YBX1 Antikörper) nuclear translocation.
findings suggest that a new player, i.e., O-GlcNAcylation, regulates hnRNP A1 translocation and interaction with Trn1, possibly affecting its function
Importins, Impbeta, Kapbeta2, Imp4 (zeige SPPL2B Antikörper), Imp5 (zeige IPO5 Antikörper), Imp7 (zeige IPO7 Antikörper), Imp9 (zeige IPO9 Antikörper), and Impalpha, show the H3 tail binding more tightly than the H4 tail. The H3 tail binds Kapbeta2 and Imp5 (zeige IPO5 Antikörper) with KD values of 77 and 57 nm, respectively, and binds the other five Importins more weakly.
Results show that Karyopherin-b2 binds to the N-terminal tail of histone H3 (zeige HIST3H3 Antikörper) with high affinity even though H3 lacks a recognizable proline-tyrosine nuclear localization signal (PY-NLS (zeige ALDH1A2 Antikörper)).
FGF2 (zeige FGF2 Antikörper) nuclear translocation is regulated by Karyopherin-beta2 and Ran GTPase (zeige RAN Antikörper) in human glioblastoma cells
Kapbeta2 interacts with ULK2 (zeige ULK2 Antikörper) through ULK2 (zeige ULK2 Antikörper)'s putative PY-NLS (zeige ALDH1A2 Antikörper) motif, and facilitates transport from the cytoplasm to the nucleus, depending on its Ser1027 residue phosphorylation by PKA, thereby reducing autophagic activity.

Mouse (Murine) Transportin 1 (TNPO1) Interaktionspartner

Co-immunoprecipitation and affinity-binding studies revealed that Rab23 (zeige RAB23 Antikörper) exists in a complex with Kif17 (zeige KIF17 Antikörper) and importin b2 implying that Kif17 (zeige KIF17 Antikörper) needs to bind to regulatory proteins like Rab23 (zeige RAB23 Antikörper) for its ciliary transport
Association with Tnpo1 is necessary for Oxtr (zeige OXTR Antikörper) nuclear localization. This is required for Oxt (zeige OXT Antikörper)-induced osteoblast differentiation. osteoblast differentiation.
DJ-1 (zeige PARK7 Antikörper) import is mediated by an oxidative stress-dependent interaction with karyopherin beta2.
Identification of a karyopherin beta1/beta2 proline-tyrosine nuclear localization signal in huntingtin (zeige HTT Antikörper) protein.
Tnpo1 is involved in a variety of functions in the adult brain, including neurogenesis, cerebrospinal fluid production and sensing, and circadian rhythms.

Xenopus laevis Transportin 1 (TNPO1) Interaktionspartner

Experiments in Xenopus assembly extracts with M9M, a superaffinity nuclear localization sequence that displaces cargoes bound by transportin, or TLB, a mutant transportin that can bind cargo and RanGTP simultaneously, support direct inhibition.

Arabidopsis thaliana Transportin 1 (TNPO1) Interaktionspartner

Results indicate that TRN1 positively regulates miRNA activity by promoting the association of miRNAs with AGO1 (zeige EIF2C1 Antikörper), and they reveal opposing roles of two importin beta (zeige KPNB1 Antikörper) family proteins in miRNA loading.
Results show that tranportin 1 (AtTRN1) recognizes a broad spectrum of proteins having diverse functions, which will potentially be the cargoes of AtTRN1.

Transportin 1 (TNPO1) Antigen-Profil

Beschreibung des Gens

This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.

Alternative names and synonyms associated with Transportin 1 (TNPO1)

transportin 1 (TNPO1) Antikörper
transportin-1 (LOC738932) Antikörper
transportin 1 (tnpo1) Antikörper
transportin 1 (Tnpo1) Antikörper
transportin 1 S homeolog (tnpo1.S) Antikörper
transportin 1 (TRN1) Antikörper

ATTRN1 Antikörper
AU021749 Antikörper
D13Ertd688e Antikörper
DKFZp469O204 Antikörper
F12A24.13 Antikörper
F12A24_13 Antikörper
IPO2 Antikörper
Kpnb2 Antikörper
MIP Antikörper
MIP1 Antikörper
TNPO1 Antikörper
transportin 1 Antikörper
TRN Antikörper

Bezeichner auf Proteinebene für anti-Transportin 1 (TNPO1) Antikörper

M9 region interaction protein , importin 2 , importin beta 2 , importin beta-2 , karyopherin (importin) beta 2 , karyopherin beta-2 , transportin-1 , transportin 1

GENE ID	SPEZIES
3842	Homo sapiens
738932	Pan troglodytes
100073294	Equus caballus
478093	Canis lupus familiaris
100101656	Xenopus (Silurana) tropicalis
427218	Gallus gallus
238799	Mus musculus
309126	Rattus norvegicus
495494	Xenopus laevis
767620	Bos taurus
816198	Arabidopsis thaliana
100171937	Pongo abelii
100735321	Cavia porcellus
100627484	Sus scrofa
100343169	Oryctolagus cuniculus
101115311	Ovis aries musimon

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