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PIP5K1A Proteine

5 Treffer:

Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (AA 1-546) protein (His tag) Protein

Synonym: phosphatidylinositol-4-phosphate 5-kinase type 1 alpha Crystallography grade PIP5K1A Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3134617
$10,832.86
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
1 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 60 Werktagen

Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (AA 1-562) protein (His tag) Protein

Synonym: phosphatidylinositol-4-phosphate 5-kinase type 1 alpha Crystallography grade PIP5K1A Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3094634
$10,832.86
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
1 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 60 Werktagen

Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (AA 1-500) protein (GST tag) Protein

Synonym: phosphatidylinositol-4-phosphate 5-kinase type 1 alpha PIP5K1A Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Produktnummer ABIN1315135
$574.29
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
10 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen

Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (AA 258-347) protein (GST tag) Protein

Synonym: phosphatidylinositol-4-phosphate 5-kinase type 1 alpha PIP5K1A Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Produktnummer ABIN1315137
$574.29
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
10 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen

Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (Active) protein (GST tag) Protein

Synonym: phosphatidylinositol-4-phosphate 5-kinase type 1 alpha PIP5K1A Spezies: Human Wirt: Insektenzellen Recombinant 70 % - 90 % Func Active
Produktnummer ABIN5509093
$340.00
Zzgl. Versandkosten $45.00
10 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 3 bis 4 Werktagen
  • Typ Protein
    • Protein
  • Target Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A)
    • Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A)
    • Hemagglutinin (HA)
    • Hemoglobin beta (HBB)
    • Ribosome Binding Factor A (RBFA)
    • Triosephosphate Isomerase 1 (TPI1)
    • S-Adenosyl-Methionine Synthase (METK)
    • Hemoglobin, alpha 1 (HBA1)
    • SARS-CoV-2 Spike
    • Myoglobin (MB)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • Thymidylate Kinase (Tmk)
    • Lipoyl synthase (lipA)
    • Growth Hormone 1 (GH1)
    • Interferon gamma (IFNG)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Aspartate Carbamoyltransferase (PYRB)
    • Uracil-DNA Glycosylase (UNG)
    • Malate Dehydrogenase (MDH)
    • Phosphoglucosamine Mutase (GLMM)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • phosphatidylserine Decarboxylase (PISD)
    • Cysteinyl-tRNA Synthetase 2, Mitochondrial (Putative) (CARS2)
    • tRNA Methyltransferase 5 (TRMT5)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Interleukin 6 (IL6)
    • Interleukin 2 (IL2)
    • Cytochrome C, Somatic (CYCS)
    • Interleukin 4 (IL4)
    • Epidermal Growth Factor Receptor (EGFR)
    • CD40 Ligand (CD40LG)
    • Gp120
    • Porphobilinogen Deaminase (HEMC)
    • Plasminogen Activator Inhibitor 1 (SERPINE1)
    • Superoxide Dismutase 1, Soluble (SOD1)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • 1-(5-Phosphoribosyl)-5-[(5-Phosphoribosylamino)methylideneamino] Imidazole-4-Carboxamide Isomerase (APG10)
    • Interleukin 10 (IL10)
    • Interleukin 8 (IL8)
    • Interleukin 1, beta (IL1B)
    • Prolactin (PRL)
    • Adenosylhomocysteinase (AHCY)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Ferrochelatase, HEMH (HEMH)
    • Thymidylate Synthase (THYA)
    • Programmed Cell Death 1 (PDCD1)
    • SARS-CoV-2 Spike S1
    • Thymidine Kinase 1, Soluble (TK1)
    • Uracil Phosphoribosyltransferase (UPP)
    • beta-2-Microglobulin (B2M)
    • Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
    • Insulin-Like Growth Factor 1 (IGF1)
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • SDS-PAGE (SDS)
    • Crystallization (Crys)
    • Functional Studies (Func)
  • Reaktivität
    • Human
    • Maus
  • Abbildungen verfügbar
  • Wirt
    • Insektenzellen
    • Wheat germ
  • Bindungsspezifität
    • AA 1-500
    • AA 1-546
    • AA 1-562
    • AA 258-347
  • Konjugat
    • Unkonjugiert
    • GST tag
    • His tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
  • Biologische Aktivität
    • Active
  • Grade
    • Crystallography grade

PIP5K1A Protein Überblick

Protein Überblick

Catalyzes the phosphorylation of phosphatidylinositol 4- phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as actin cytoskeleton organization, cell adhesion, migration and phagocytosis. Required for membrane ruffling formation, actin organization and focal adhesion formation during directional cell migration by controlling integrin-induced translocation of RAC1 to the plasma membrane. Together with PIP5K1C is required for phagocytosis, but they regulate different types of actin remodeling at sequential steps. Promotes particle ingestion by activating WAS that induces Arp2/3 dependent actin polymerization at the nascent phagocytic cup. Together with PIP5K1B is required after stimulation of G-protein coupled receptors for stable platelet adhesion. Plays a role during calcium-induced keratinocyte differentiation. Recruited to the plasma membrane by the E-cadherin/beta-catenin complex where it provides the substrate PtdIns(4,5)P2 for the production of PtdIns(3,4,5)P3, diacylglycerol and inositol 1,4,5-trisphosphate that mobilize internal calcium and drive keratinocyte differentiation. Together with PIP5K1C have a role during embryogenesis. Functions also in the nucleus where acts as an activator of TUT1 adenylyltransferase activity in nuclear speckles, thereby regulating mRNA polyadenylation of a select set of mRNAs.

Alternative names and synonyms associated with PIP5K1A

  • phosphatidylinositol-4-phosphate 5-kinase type 1 alpha (PIP5K1A) Antikörper
  • phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha (Pip5k1a) Antikörper
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha L homeolog (pip5k1a.L) Antikörper
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha (pip5k1a) Antikörper
  • phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha (Pip5k1a) Antikörper
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a (pip5k1aa) Antikörper
  • phosphatidylinositol-4-phosphate 5-kinase type 1 alpha (Pip5k1a) Antikörper
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b (pip5k1ab) Antikörper
  • im:7140933 Antikörper
  • pip5k1a Antikörper
  • pip5k1b Antikörper
  • pip5k1c Antikörper
  • Pipk5a Antikörper
  • Pipk5b Antikörper
  • zgc:110576 Antikörper
  • zgc:158838 Antikörper

Bezeichner auf Proteinebene für PIP5K1A

68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha , 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha , PIP5K1-alpha , PIP5KIalpha , phosphatidylinositol 4-phosphate 5-kinase type I alpha , phosphatidylinositol 4-phosphate 5-kinase type-1 alpha , phosphatidylinositol-4-phosphate 5-kinase type-1 alpha , ptdIns(4)P-5-kinase 1 alpha , phosphatidylinositol-4-phosphate 5-kinase, type 1 beta , phosphatidylinositol-4-phosphate 5-kinase, type I, alpha , phosphatidylinositol-4-phosphate 5-kinase, type I, beta , 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase , 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase , PI4P5K-I[a] , PI4P5KIbeta , phosphatidylinositol 4-phosphate 5-kinase type I beta , phosphatidylinositol-4-phosphate 5-kinase type I alpha , phosphatidylinositol-4-phosphate 5-kinase type I beta , phosphatidylinositol-4-phosphate 5-kinase type-1 gamma

GENE ID SPEZIES
8394 Homo sapiens
365865 Rattus norvegicus
399203 Xenopus laevis
429983 Gallus gallus
448746 Xenopus (Silurana) tropicalis
457288 Pan troglodytes
475846 Canis lupus familiaris
710007 Macaca mulatta
100017950 Monodelphis domestica
100059655 Equus caballus
100125224 Bos taurus
100137415 Papio anubis
18720 Mus musculus
553629 Danio rerio
100715277 Cavia porcellus
492549 Danio rerio

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