MAP3K8 ELISA Kits

Protein Überblick

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.

Alternative names and synonyms associated with MAP3K8

• mitogen-activated protein kinase kinase kinase 8 (MAP3K8) Antikörper
• mitogen-activated protein kinase kinase kinase 8 (map3k8) Antikörper
• mitogen-activated protein kinase kinase kinase 8 (Map3k8) Antikörper

• c-COT Antikörper
• Cot Antikörper
• Cot/Tpl2 Antikörper
• D17TPL2 Antikörper
• Est Antikörper
• Alle Synonyme
• Estf Antikörper
• MAP3K8 Antikörper
• MEKK8 Antikörper
• Tpl-2 Antikörper
• Tpl2 Antikörper

Bezeichner auf Proteinebene für MAP3K8

mitogen-activated protein kinase kinase kinase 8 , Ewing sarcoma transformant , cot (cancer Osaka thyroid) oncogene , proto-oncogene c-Cot , proto-oncogene serine/threoine protein kinase , tumor progression locus 2 , COT proto-oncogene serine/threonine-protein kinase , cancer Osaka thyroid oncogene , cancer Osaka thyroid, oncogene , mitogen activated protein kinase kinase kinase 8 , serine/threonine-protein kinase cot , serine/threonine kinase (Tpl-2)