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Rat (Rattus) FOXO1 ELISA Kit für Sandwich ELISA - ABIN431805
Akbulut, Aktas, Akbulut: The role of melatonin, sirtuin2 and FoXO1 transcription factor in the aging process of colon in male rats. in Biogerontology 2015
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miR (zeige MLXIP ELISA Kits)-181a2/181b2 prominently dampened cell-cycle progression, suppressed cell growth, and promoted apoptosis of tumor cells in vitro They also effectively impeded tumor formation and growth in vivo miR (zeige MLXIP ELISA Kits)-181a2/181b2 exert the tumor suppressor ability by depressing the direct target PIK3R3 (p55gamma) and consequently modulating the PIK3R3/Akt (zeige AKT1 ELISA Kits)/FoxO (zeige FOXO3 ELISA Kits) signaling pathway
A high extent more than 25% of BRAF (zeige BRAF ELISA Kits)(V600E) alleles may be associated with disease outcome in PTC (zeige F9 ELISA Kits) patients.
Low FOXO1 expression is associated with hepatocellular carcinoma.
Combined treatment with gamma-irradiation (gammaIR) and a dual PI3K (zeige PIK3CA ELISA Kits)/mTOR (zeige FRAP1 ELISA Kits) inhibitor causes loss of stemness and of FoxO1/3 proteins in p53 (zeige TP53 ELISA Kits)-proficient glioblastoma multiforme stem cells (GBM-SCs (zeige TWIST1 ELISA Kits)).
AQP9 (zeige AQP7 ELISA Kits) overexpression decreased the protein levels of phosphatidylinositol-3-kinase (PI3K (zeige PIK3CA ELISA Kits)), leading to reduced phosphorylation of Akt (zeige AKT1 ELISA Kits), and subsequently the protein levels of forkhead box protein O1 (FOXO1) were increased.
High glucose triggers IL-1beta (zeige IL1B ELISA Kits) synthesis in retinal endothelial cells. The produced IL-1beta (zeige IL1B ELISA Kits) induces increased FoxO1 expression, and interacts with the IL-1 (zeige IL1A ELISA Kits) receptor to activate MAPK (zeige MAPK1 ELISA Kits) signaling, thereby inducing IL-1beta (zeige IL1B ELISA Kits) autostimulation.
Results identified FOXO1 as a downstream effector of DKK3 that may play a role in blocking adrenocortical dedifferentiation.
Foxo1 signaling contributes to maintainance and exacerbation inflammation and insulin (zeige INS ELISA Kits) resistance in polycystic ovary syndrome macrophages.
presence of a new non-consensus FoxO1 binding site on the G6PC1 (zeige G6PC ELISA Kits) promoter that overlaps the CRE, suggesting a mutual exclusion mechanism for FoxO1 and CREB (zeige CREB1 ELISA Kits) binding at the G6PC1 (zeige G6PC ELISA Kits) promoter
These results indicate that miR (zeige MYLIP ELISA Kits)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.
gas6 (zeige GAS6 ELISA Kits) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (zeige AKT1 ELISA Kits)-dependent inactivation of FOXO1a.
we found that in db/db (zeige LEPR ELISA Kits) VSMC, the occupancy in promoter regions of inflammatory genes by FOXO1 was reduced.miR-135a increased the inflammatory responses of VSMC involved in complications of vascular diseases by downregulating the expression of FOXO1.
Trehalose may rescue against insulin (zeige INS ELISA Kits) resistance-induced myocardial contractile defect and apoptosis, via autophagy associated with dephosphorylation of p38 MAPK (zeige MAPK14 ELISA Kits) and Foxo1 without affecting phosphorylation of Akt (zeige AKT1 ELISA Kits).
FoxO1 is a key mediator involved in glucose homeostasis and indicate that 1,25(OH)2D3 improves glucose metabolism and bone development
Data show that the mitochondrial enriched GCN5 (zeige KAT2A ELISA Kits)-like 1 protein (GCN5L1 (zeige BLOC1S1 ELISA Kits)) controls hepatic glucose production by regulating FoxO1 protein levels.
Setdb1 (zeige SETDB1 ELISA Kits) regulates PTEN/AKT (zeige AKT1 ELISA Kits)/FOXO1 pathway to inhibit Spermatogonial stem cells apoptosis.
These findings indicate that IGF-II reduces PGC-1alpha (zeige PPARGC1A ELISA Kits) expression in skeletal muscle cells through a mechanism involving PI3K-Akt (zeige AKT1 ELISA Kits)-FoxO1 but not p38 MAPK (zeige MAPK14 ELISA Kits) or Erk1/2 (zeige MAPK1/3 ELISA Kits) MAPK (zeige MAPK1 ELISA Kits) pathways.
a critical role for FOXO (zeige FOXO3 ELISA Kits) transcription factors in mediating these proliferative versus apoptotic fates
L. donovani triggered AKT (zeige AKT1 ELISA Kits) activation to regulate GSK-3beta (zeige GSK3b ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits)/FOXO-1 axis.
The data suggest autocrine nitric oxide/atrial natriuretic peptide (zeige NPPA ELISA Kits)-induced activation of protein kinase (zeige CDK7 ELISA Kits) G type Ialpha/p-AKT (zeige AKT1 ELISA Kits)/p-FOXO1 promotes survival and proliferation in pancreatic beta-cells.
Myocardial ischemia is associated with downregulation and posttranslational modification of cardiac FoxO1. In a mouse model of postischemic heart failure, posttranslational modulation of FoxO1 alters heart function involving collagen and protein metabolism.
These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (zeige AKT1 ELISA Kits)-mTOR (zeige FRAP1 ELISA Kits)-FOXO1 signaling and suppressing the activation of TLR4 (zeige TLR4 ELISA Kits) and/or NOD2 (zeige NOD2 ELISA Kits) signaling pathways.
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (zeige MAP3K1 ELISA Kits) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.
inhibition of FoxO1 expression level caused by miR (zeige MYLIP ELISA Kits)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (zeige MYLIP ELISA Kits)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1
Results show that FoxO1 likely regulates MyHC I (zeige MYH7 ELISA Kits) negatively and MyHC IIx and MyHC IIb (zeige MYH4 ELISA Kits) positively and may play a pivotal role in the determination of muscle fiber type.
Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (zeige TNFSF10 ELISA Kits) and Fas ligand FasL (zeige FASL ELISA Kits) expression during follicular atresia.
Data show that IL-4 (zeige IL4 ELISA Kits) induces upregulation of the junction protein claudin-5 (zeige CLDN5 ELISA Kits) in endothelial cells (ECs) through activation of Jak (zeige JAK3 ELISA Kits)/STAT6 (zeige STAT6 ELISA Kits) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.
FoxO1 and C/EBPb (zeige CEBPB ELISA Kits) regulate preadipocyte adipogenesis possibly through C/EBPb (zeige CEBPB ELISA Kits)-> FoxO1-> C/EBPb (zeige CEBPB ELISA Kits) feedback regulatory loop and FoxO1-C/EBPb (zeige CEBPB ELISA Kits) protein complex.
FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.
concluded that PI 3 (zeige PI3 ELISA Kits)-kinase and Akt (zeige AKT1 ELISA Kits) are activated after renal ischemia/reperfusion and that Akt (zeige AKT1 ELISA Kits) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (zeige FOXO3 ELISA Kits), which may affect epithelial cell fate in acute renal failure.
FoxO1a can regulate p27kip nuclear localization
MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.
downregulation of SIRT1 (zeige SIRT1 ELISA Kits) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age
FOXO (zeige FOXO3 ELISA Kits) is a key regulator of ROS (zeige ROS1 ELISA Kits)-induced apoptosis in mammalian cells.
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (zeige NCAM1 ELISA Kits)-1 mRNA.
The results demonstrate pathways through which two different mediators, TNF-alpha (zeige TNF ELISA Kits) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.
FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (zeige SOD1 ELISA Kits) and catalase (zeige CAT ELISA Kits) mRNA and protein levels in this organ.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
forkhead box protein O1
, forkhead box protein O1A
, forkhead, Drosophila, homolog of, in rhabdomyosarcoma
, forkhead box O1A
, forkhead box protein O1-A
, fox family transcription factor FoxO1a.1
, foxhead box protein O1-A
, Forkhead box protein O1A
, Forkhead in rhabdomyosarcoma
, forkhead box O1A (rhabdomyosarcoma)
, forkhead box O1a
, forkhead in rhabdomyosarcoma
, forkhead protein 1
, forkhead/winged helix transcription factor FOXO1a
, forkhead box O1
, forkhead box protein O1-like