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Cow (Bovine) Monoclonal Cyclin A Primary Antibody für ICC, WB - ABIN3043070
Zhao, Li, Gao, Wang, Yan, Zhan, Liu, Mao, Chen, Wang et al.: Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3? (GSK-3?) ... in European journal of medicinal chemistry 2014
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Human Polyclonal Cyclin A Primary Antibody für ICC, IF - ABIN441337
Pan, Nakade, Huang, Zhu, Masuzaki, Hasegawa, Murata, Yoshiki, Yamaguchi, Lee, Yang, Tsai, Obata, Yokoyama: Suppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2. in Oncogene 2010
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Human Polyclonal Cyclin A Primary Antibody für ChIP, ICC - ABIN4301457
Mazurek, Luo, Krasnitz, Hicks, Powers, Stillman: DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells. in Cancer discovery 2012
Human Polyclonal Cyclin A Primary Antibody für IF (p), IHC (p) - ABIN670281
Zhang, Pan, Xu, Niu, Ma, Xu: Interleukin 18 augments growth ability via NF-?B and p38/ATF2 pathways by targeting cyclin B1, cyclin B2, cyclin A2, and Bcl-2 in BRL-3A rat liver cells. in Gene 2015
Study demonstrates that cyclin A2 interacts with actin and RhoA (zeige RHOA Antikörper) during mitosis, and that cyclin A2 depletion induces a dramatic decrease in active RhoA (zeige RHOA Antikörper) in mitosis suggesting that cyclin A2 participation in RhoA (zeige RHOA Antikörper) activation in late mitosis.
Bisphosphonate inhibits the expression of cyclin A2 at the transcriptional level in normal human oral keratinocytes.
the presented evidence suggested that WA can inhibit HCC (zeige FAM126A Antikörper) cell proliferationand tumorigenesis through miR (zeige MLXIP Antikörper)-22-repressed CCNA2, which was at least partially through FXR (zeige NR1H4 Antikörper) regulation
Findings suggest that ERK1/2-mediated Cdk2 (zeige CDK2 Antikörper)/cyclin A signaling pathway is involved in 7-hydroxy-5,4'-dimethoxy-2-arylbenzofuran (Ary) - induced G1/S-phase arrest.
some cancer cells are defective for efficient interaction between p27 (zeige PAK2 Antikörper) and CycA-CDK (zeige CDK4 Antikörper) complex due to qualitative alteration(s)
This study shows that cocaine induces significant increases in both the astrocytic expression of cyclin A2 and the proliferation of primary human astrocytes.
Low CCNA expression is associated with lung cancer progression.
cyclin D1 (zeige CCND1 Antikörper) and other cyclins such as cyclin A regulates DNA integrity through RAD51 (zeige RAD51 Antikörper) interaction with the BRCA2 (zeige BRCA2 Antikörper) C-terminal domain
inhibition of PDK4 (zeige PDK4 Antikörper) activity in Hepatocellular carcinoma cells increased cyclin E1 (zeige CCNE1 Antikörper), cyclin A2, and E2F1 (zeige E2F1 Antikörper) proteins.
An increase of cyclin A2 expression was identified for the first time in a case of splenic diffuse red pulp small B-cell lymphoma.
We demonstrate that CCNA2-null progenitors suffer abnormal DNA repair, and implicate Cyclin A2 in double-strand break repair. Cyclin A2's DNA repair functions are conserved among cell lines, neural progenitors, and hippocampal neurons. We further demonstrate that neuronal CCNA2 ablation results in learning and memory deficits in aged mice.
cyclin A2 mediates the fidelity ofmeiosis II by maintaining microtubule dynamics during the rapid formation of the meiosis II spindle.
These data unveils the critical functions of cyclin A2 in regulating mammalian erythropoiesis.
Meioc-deficient spermatocytes that have initiated synapsis mis (zeige AMH Antikörper)-express CYCLIN A2, which is normally expressed in mitotic spermatogonia, suggesting a failure to properly transition to a meiotic cell cycle program.
cyclin A2 controlled Mre11 (zeige MRE11A Antikörper) abundance through a C-terminal RNA binding domain that selectively and directly binds Mre11 (zeige MRE11A Antikörper) transcripts to mediate polysome loading and translation.
hese data suggest that mmu-miR (zeige MLXIP Antikörper)-125b decreases NO production in activated macrophages at least partially by suppressing eEF2K (zeige EEF2K Antikörper) and CCNA2 expression.
Cyclin A2 modulates epithelial-mesenchymal transition via beta-catenin (zeige CTNNB1 Antikörper) and phospholipase C (zeige PLC Antikörper) pathways.
Ccn2 (zeige CTGF Antikörper) is a regulator of the transition through cytokinesis during terminal erythropoiesis.
Loss of CCNA2 decreases cell proliferation and induces cerebellar cortical dyslamination.
an essential role for UHRF1 (zeige UHRF1 Antikörper) phosphorylation by cyclin-dependent kinase 2 (zeige CDK2 Antikörper)/cyclin A2 during early vertebrate development
B-Myb (zeige MYBL2 Antikörper) represses SMC (zeige DYM Antikörper) elastin (zeige ELN Antikörper) gene expression and cyclin A plays a role in the developmental regulation of elastin (zeige ELN Antikörper) gene expression in the aorta
inconstant elongation of the poly(A) tail was observed for cyclin A2 transcripts after maturation
The two single nucleotide polymorphisms of the CCNA2 gene affect wool density in the Rex rabbit.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
, cyclin A
, Cyclin A2 (Cyclin A)
, cyclin A1
, cyclin A2