This is a synthetic peptide designed for use in combination with anti-Wdr5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Wdr5 contributes to histone modification. It may position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It may regulate osteoblasts differentiation.
Alias Symbols: 2410008O07Rik, AA408785, AA960360, Big, Big-3
Protein Interaction Partner: Esrrb,Kdm2b,Nr0b1,Pou5f1,Rnf2,Sall4,Tcfcp2l1