Vesicle-Associated Membrane Protein 7 (VAMP7) (C-Term) Peptid
VAMP7
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN986022
Kurzübersicht für Vesicle-Associated Membrane Protein 7 (VAMP7) (C-Term) Peptid (ABIN986022)
Target
VAMP7
(Vesicle-Associated Membrane Protein 7 (VAMP7))
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- DELKGIMVRN IDLVAQRGER LELLIDKTEN LVDSSVTFKT TSRNLARAMC
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Vamp7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))
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Hintergrund
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Vamp7 is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Vamp7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion.Vamp7 is required for calcium regulated lysosomal exocytosis. Vamp7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi.Vamp7 is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Vamp7 is also required for focal exocytosis of late endocytic vesicles during phagosome formation.
Alias Symbols: Sybl1, TI-VAMP, VAMP-7
Protein Interaction Partner: Stx7
Protein Size: 220 -
Molekulargewicht
- 25 kDa
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Gen-ID
- 20955
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NCBI Accession
- NM_011515, NP_035645
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UniProt
- P70280
Target
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