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Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (N-Term) Peptid

UBE2V1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN985843

Kurzübersicht für Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (N-Term) Peptid (ABIN985843)

Target

UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    GEVQASYLKS QSKLSDEGRL EPRKFHCKGV KVPRNFRLLE ELEEGQKGVG

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-UBE2V1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

    Hintergrund

    Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

    Alias Symbols: CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A

    Protein Interaction Partner: KITLG,SUMO4,UBE2N,ARIH2,BIRC8,DTX3,DZIP3,MID1,MKRN3,RNF10,RNF111,RNF14,RNF144A,RNF185,RNF2,RNF5,STUB1,Stub1,TRAF2,TRAF6,TRIM32,TRIM39,TRIM5,TRIM8,UBE2N,UBOX5,XIAP,ZNRF1

    Protein Size: 170

    Molekulargewicht

    19 kDa

    Gen-ID

    7335

    NCBI Accession

    NM_021988, NP_068823

    UniProt

    Q13404
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