Tripartite Motif Containing 23 (TRIM23) (Middle Region) Peptid
TRIM23
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN985498
Kurzübersicht für Tripartite Motif Containing 23 (TRIM23) (Middle Region) Peptid (ABIN985498)
Target
TRIM23
(Tripartite Motif Containing 23 (TRIM23))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TRIM23 antibody (Catalog #: ARP32672_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM23 (Tripartite Motif Containing 23 (TRIM23))
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Hintergrund
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TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Alias Symbols: ARD1, ARFD1, RNF46
Protein Interaction Partner: C19orf57,CYTH1,CYTH2,FLAD1,GEM,GGA2,LNX1,POM121,RIBC2,SF1,TRIM23,TRIM27,TRIM29,TRIM31,ZNF250,ZNF581,C19orf57,CYTH1,CYTH2,FLAD1,GEM,GGA2,LNX1,POM121,RIBC2,SF1,TRIM23,TRIM27,TRIM28,TRIM29,TRIM31,TRIM32,TRIM6,ZNF250,ZNF581
Protein Size: 546 -
Molekulargewicht
- 61 kDa
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Gen-ID
- 373
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NCBI Accession
- NM_033228, NP_150231
Target
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