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TRAF3 Interacting Protein 2 (TRAF3IP2) (N-Term) Peptid

TRAF3IP2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN985438

Kurzübersicht für TRAF3 Interacting Protein 2 (TRAF3IP2) (N-Term) Peptid (ABIN985438)

Target

TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    IPVEVDESEP YPSQLLKPIP EYSPEEESEP PAPNIRNMAP NSLSAPTMLH

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-TRAF3IP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

    Hintergrund

    This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

    Alias Symbols: ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZp586G0522, MGC3581, PSORS13

    Protein Size: 574

    Molekulargewicht

    65 kDa

    Gen-ID

    10758

    NCBI Accession

    NM_147200, NP_671733

    UniProt

    O43734
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