Transmembrane Protease, serine 6 (TMPRSS6) (N-Term) Peptid
TMPRSS6
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
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- Target Alle TMPRSS6 Produkte
- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TMPRSS6 antibody (Catalog #: ARP53188_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
- Synonyme
- IRIDA Peptide, 1300008A22Rik Peptide, transmembrane protease, serine 6 Peptide, transmembrane serine protease 6 Peptide, Tmprss6 Peptide, TMPRSS6 Peptide
- Hintergrund
-
TMPRSS6 is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. TMPRSS6 can also activate urokinase-type plasminogen activator with low efficiency. TMPRSS6 may play a specialized role in matrix remodeling processes in liver. TMPRSS6 is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses activation of the HAMP promoter.The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.
Alias Symbols: IRIDA
Protein Interaction Partner: COL1A1,FN1,LAMA1
Protein Size: 811 - Molekulargewicht
- 90 kDa
- Gen-ID
- 164656
- NCBI Accession
- NM_153609, NP_705837
- UniProt
- Q8IU80
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