Transmembrane Protein 173 (TMEM173) (Middle Region) Peptid
TMEM173
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle STING/TMEM173 (TMEM173) Produkte
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Protein Region
- Middle Region
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TMEM173 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Hintergrund
-
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Alias Symbols: ERIS, MITA, MPYS, SAVI, NET23, STING, hMITA, hSTING
Protein Size: 379 - Molekulargewicht
- 42 kDa
- Gen-ID
- 340061
- NCBI Accession
- NM_198282, NP_938023
- UniProt
- Q86WV6
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