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Toll-Like Receptor 8 (TLR8) (C-Term) Peptid

TLR8 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN985141

Kurzübersicht für Toll-Like Receptor 8 (TLR8) (C-Term) Peptid (ABIN985141)

Target

TLR8 (Toll-Like Receptor 8 (TLR8))

Spezies

Human

Quelle

  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    LEPVLQHSQY LRLRQRICKS SILQWPDNPK AEGLFWQTLR NVVLTENDSR

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-TLR8 Antibody(ARP59048_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    TLR8 (Toll-Like Receptor 8 (TLR8))

    Hintergrund

    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

    Alias Symbols: CD288, MGC119599, MGC119600

    Protein Interaction Partner: BTK,MYD88

    Protein Size: 1041

    Molekulargewicht

    120 kDa

    Gen-ID

    51311

    NCBI Accession

    NM_138636, NP_619542

    UniProt

    Q9NR97
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