Thymocyte Selection Associated (THEMIS) (C-Term) Peptid
Kurzübersicht für Thymocyte Selection Associated (THEMIS) (C-Term) Peptid (ABIN985055)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Sequenz
- RHHVDITKKL HPNQAGLDSK VLIGSQNDLV DEEKERSNRG ATAIAETFKN
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-THEMIS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- THEMIS (Thymocyte Selection Associated (THEMIS))
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Hintergrund
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THEMIS plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. It is required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. It regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
Alias Symbols: C6orf190, C6orf207, FLJ40584, MGC163388, TSEPA, bA325O24.3, bA325O24.4, GASP, SPOT
Protein Size: 606 -
Molekulargewicht
- 66 kDa
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Gen-ID
- 387357
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NCBI Accession
- NM_001164687, NP_001158159
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UniProt
- Q8N1K5
Target
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