Thymocyte Selection Associated (THEMIS) (C-Term) Peptid
THEMIS
Reaktivität: Human
Wirt: Synthetic
BP, WB
-
- Target Alle THEMIS Produkte
- THEMIS (Thymocyte Selection Associated (THEMIS))
- Protein Region
- C-Term
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- RHHVDITKKL HPNQAGLDSK VLIGSQNDLV DEEKERSNRG ATAIAETFKN
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-THEMIS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- THEMIS (Thymocyte Selection Associated (THEMIS))
- Hintergrund
-
THEMIS plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. It is required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. It regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
Alias Symbols: C6orf190, C6orf207, FLJ40584, MGC163388, TSEPA, bA325O24.3, bA325O24.4, GASP, SPOT
Protein Size: 606 - Molekulargewicht
- 66 kDa
- Gen-ID
- 387357
- NCBI Accession
- NM_001164687, NP_001158159
- UniProt
- Q8N1K5
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