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Testis Derived Transcript (3 LIM Domains) (TES) (Middle Region) Peptid

TES Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN984960
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Testis Derived Transcript (3 LIM Domains) (TES) (Middle Region) Peptid (ABIN984960)

Target

TES (Testis Derived Transcript (3 LIM Domains) (TES))

Spezies

Human

Quelle

Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    PKQMNIPGGD RSTPAAVGAM EDKSAEHKRT QYSCYCCKLS MKEGDPAIYA

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-TES Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    TES (Testis Derived Transcript (3 LIM Domains) (TES))

    Hintergrund

    Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.

    Alias Symbols: DKFZp586B2022, MGC1146, TESS, TESS-2

    Protein Interaction Partner: ACTL7A,ENAH,EVL,GRIP1,SPTAN1,TES,TLN1,VASP,ACTL7A,ACTN1,ENAH,EVL,GRIPAP1,SPOCK2,SPTAN1,TES,TLN1,VASP,ZYX,ACTA1,ENAH,RAB8B,VASP,ZYX

    Protein Size: 421

    Molekulargewicht

    46 kDa

    Gen-ID

    26136

    NCBI Accession

    NM_015641, NP_056456

    UniProt

    Q9UGI8
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