Testis Derived Transcript (3 LIM Domains) (TES) (Middle Region) Peptid
Kurzübersicht für Testis Derived Transcript (3 LIM Domains) (TES) (Middle Region) Peptid (ABIN984960)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Sequenz
- PKQMNIPGGD RSTPAAVGAM EDKSAEHKRT QYSCYCCKLS MKEGDPAIYA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TES Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TES (Testis Derived Transcript (3 LIM Domains) (TES))
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Hintergrund
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Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
Alias Symbols: DKFZp586B2022, MGC1146, TESS, TESS-2
Protein Interaction Partner: ACTL7A,ENAH,EVL,GRIP1,SPTAN1,TES,TLN1,VASP,ACTL7A,ACTN1,ENAH,EVL,GRIPAP1,SPOCK2,SPTAN1,TES,TLN1,VASP,ZYX,ACTA1,ENAH,RAB8B,VASP,ZYX
Protein Size: 421 -
Molekulargewicht
- 46 kDa
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Gen-ID
- 26136
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NCBI Accession
- NM_015641, NP_056456
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UniProt
- Q9UGI8
Target
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