HNF1 Homeobox B (HNF1B) Peptid
HNF1B
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN984890
Kurzübersicht für HNF1 Homeobox B (HNF1B) Peptid (ABIN984890)
Target
HNF1B
(HNF1 Homeobox B (HNF1B))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TCF2 antibody (Catalog #: ARP32320_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNF1B (HNF1 Homeobox B (HNF1B))
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Hintergrund
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TCF2 encodes transcription factor 2, a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5).
Alias Symbols: FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
Protein Interaction Partner: ATF1,CREBBP,HNF1A,ATF1,CREB1,HNF1A
Protein Size: 399 -
Molekulargewicht
- 45 kDa
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Gen-ID
- 6928
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NCBI Accession
- NM_006481, NP_006472
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UniProt
- P35680
Target
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