Transcription Elongation Factor A (SII), 3 (TCEA3) (C-Term) Peptid
Kurzübersicht für Transcription Elongation Factor A (SII), 3 (TCEA3) (C-Term) Peptid (ABIN984868)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Sequenz
- LKDPRNPGLR RNVLSGAISP ELIAKMTAEE MASDELRELR NAMTQEAIRE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Tcea3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TCEA3 (Transcription Elongation Factor A (SII), 3 (TCEA3))
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Hintergrund
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Tcea3 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
Alias Symbols: S-II, SII-K1
Protein Size: 347 -
Molekulargewicht
- 39 kDa
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Gen-ID
- 21401
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NCBI Accession
- NM_011542, NP_035672
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UniProt
- P23881
Target
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