TBP-Like 1 (TBPL1) Peptid
TBPL1
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN984812
Kurzübersicht für TBP-Like 1 (TBPL1) Peptid (ABIN984812)
Target
TBPL1
(TBP-Like 1 (TBPL1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TBPL1 antibody (Catalog #: ARP35751_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TBPL1 (TBP-Like 1 (TBPL1))
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Hintergrund
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TBPL1 encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
Alias Symbols: TLF, TLP, STUD, TRF2, MGC:8389, MGC:9620
Protein Interaction Partner: ABCF3,C2orf18,GTF2A1,GTF2A2,GTF2B,IRAK4,NDUFA6,NF1,PLIN3,PTCD3,RAB35,RPL10,GTF2A1,GTF2A2,GTF2B,HSPA9,NDUFA6,PMVK,RAB35,RPL10,TAF1,TAF1L,TAF4,TAF5,TAF6,TBP,TBPL2
Protein Size: 186 -
Molekulargewicht
- 21 kDa
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Gen-ID
- 9519
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NCBI Accession
- NM_004865, NP_004856
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UniProt
- P62380
Target
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