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TBP-Like 1 (TBPL1) Peptid

TBPL1 Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN984812
  • Target Alle TBPL1 Produkte
    TBPL1 (TBP-Like 1 (TBPL1))
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-TBPL1 antibody (Catalog #: ARP35751_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TBPL1 (TBP-Like 1 (TBPL1))
    Hintergrund
    Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TBPL1 encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.

    Alias Symbols: TLF, TLP, STUD, TRF2, MGC:8389, MGC:9620

    Protein Interaction Partner: ABCF3,C2orf18,GTF2A1,GTF2A2,GTF2B,IRAK4,NDUFA6,NF1,PLIN3,PTCD3,RAB35,RPL10,GTF2A1,GTF2A2,GTF2B,HSPA9,NDUFA6,PMVK,RAB35,RPL10,TAF1,TAF1L,TAF4,TAF5,TAF6,TBP,TBPL2

    Protein Size: 186
    Molekulargewicht
    21 kDa
    Gen-ID
    9519
    NCBI Accession
    NM_004865, NP_004856
    UniProt
    P62380
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