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TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) Peptid

TBC1D10C Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN984785

Kurzübersicht für TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) Peptid (ABIN984785)

Target

Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))

Spezies

Human

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-TBC1D10C antibody (Catalog #: ARP55893_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))

    Hintergrund

    TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM].

    Alias Symbols: FLJ00332, MGC46488, EPI64C, CARABIN

    Protein Interaction Partner: PPP3R2

    Protein Size: 446

    Molekulargewicht

    50 kDa

    Gen-ID

    374403

    NCBI Accession

    NM_198517, NP_940919

    UniProt

    Q8IV04
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