SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Peptid
SWAP70
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN984655
Kurzübersicht für SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Peptid (ABIN984655)
Target
SWAP70
(SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SWAP70 antibody (Catalog #: ARP46214_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
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Hintergrund
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Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Alias Symbols: FLJ39540, HSPC321, KIAA0640, SWAP-70
Protein Interaction Partner: CELSR3,IGHG1,PARP1,NCL,NPM1,PARP1
Protein Size: 585 -
Molekulargewicht
- 69 kDa
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Gen-ID
- 23075
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NCBI Accession
- NM_015055, NP_055870
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UniProt
- Q9UH65
Target
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