Sulfatase 2 (SULF2) Peptid
SULF2
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN984614
Kurzübersicht für Sulfatase 2 (SULF2) Peptid (ABIN984614)
Target
SULF2
(Sulfatase 2 (SULF2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SULF2 antibody (Catalog #: ARP49338_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SULF2 (Sulfatase 2 (SULF2))
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Hintergrund
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Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM].
Alias Symbols: DKFZp313E091, FLJ90554, HSULF-2, KIAA1247, MGC126411
Protein Size: 870 -
Molekulargewicht
- 98 kDa
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Gen-ID
- 55959
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NCBI Accession
- NM_018837, NP_061325
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UniProt
- Q8IWU5
Target
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