Serum Response Factor (SRF) Peptid
SRF
Reaktivität: Human, Maus
Wirt: Synthetic
BP, ChIP, WB
Produktnummer ABIN984414
Kurzübersicht für Serum Response Factor (SRF) Peptid (ABIN984414)
Target
SRF
(Serum Response Factor (SRF))
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SRF antibody (Catalog #: P100866_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SRF (Serum Response Factor (SRF))
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Hintergrund
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SRF is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).
Alias Symbols: MCM1
Protein Interaction Partner: FHL1,FHL2,FHL3,FHL5,FOS,FOSL1,NFYA,ATF6,BARX2,CAMK2A,CASP3,CASP6,CASP7,CASP8,CASP9,CEBPB,CREB1,CREBBP,CRIP2,CSNK2A1,ELK1,ELK4,ETV4,FHL1,FHL2,FHL3,FHL5,FLI1,GATA4,GTF2F1,GTF2I,HMGA1,HOPX,MAPKAPK2,MINPP1,MKL1,MKL2,MYOCD,MYOD1,MYOG,NCOA1,NCOR2,NFYA,NKX2-3,NKX2-5,NKX3-1,OGT,PML,PRKDC,PRRX1,PYCARD,RELA,RPS6KA1,RXRA,RXRG,SRC,SRF,SRFBP1,SSRP1,TCF3,TEAD1,ASCC1,ASCC2,ASCC3,ATF6,CD63,CEBPB,CREBBP,ELK1,ELK4,FLI1,GATA4,GTF2F1,GTF2I,Gata2,Gata4,Gata6,Hmga1,Hmga2,MKL1,MKL2,MYOCD,MYOG,Mkl1,Mkl2,Myocd,NCOA6,NCOR2,NFYA,NKX3-1,Nkx2-5,PML,RARG,REL,RELA,RXRG,SMARCA4,SP1,SRC,SSRP1,Ssrp1,TEAD1
Protein Size: 508 -
Molekulargewicht
- 52 kDa
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Gen-ID
- 6722
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NCBI Accession
- NM_003131, NP_003122
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UniProt
- P11831
Target
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