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Proto-oncogene tyrosine-protein kinase Src (Src) (N-Term) Peptid

Src Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN984404
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 21 Werktagen

Kurzübersicht für Proto-oncogene tyrosine-protein kinase Src (Src) (N-Term) Peptid (ABIN984404)

Target

Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Spezies

Human

Quelle

  • 10
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-SRC antibody (Catalog #: ARP32475_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Src (Proto-oncogene tyrosine-protein kinase Src (Src))

    Substanzklasse

    Viral Protein

    Hintergrund

    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

    Alias Symbols: ASV, SRC1, c-SRC, p60-Src

    Protein Interaction Partner: E2F4,ABL1,BCAR1,BCR,CDCP1,DRD4,ERBB2,ETS1,ETS2,GJA1,GJB1,HNRNPK,KHDRBS1,MUC1,PDE4D,PDGFRB,PTK2,PTK2,PTPN2,RGS16,SHB,SHC1,SRC,ABL1,ACTN1,ADAM12,ADAM15,ADRB2,ADRB3,ADRBK1,AFAP1,AFAP1L2,AKT1,ANKRD11,ANXA1,ANXA2,AR,ARHGAP1,ARHGAP32,ARR3,ASAP1,ATP2B4,AXL,BCAR1,BCR,BMX,CAV1,CAV2,CBL,CBLC,CD2AP,CD33,CD36,CD46,CD59,CDCP1,CDH5,CDK5,CDKN1B,CEACAM1,CEACAM3,CHUK,CNTNAP1,CSK,CTNNB1,CTNND1,CTTN,DAB1,DAB2,DAG1,DAPP1,DDR2,DGKA,DGKZ,DLG4,DNM1,DNM2,DOK1,DOK2,DOK4,EFNB1,EFNB2,EGFR,EPHB2,EPS8,ERBB2,ESR1,ESR2,ETS1,ETS2,EVL,FARP2,FASLG,FGR,FHIT,FOXO1,FRS2,FYB,GAB2,GAB3,GFAP,GIT1,GJA1,GJB1,GNB2L1,GRB10,GRB2,GRIN2A,GRIN2B,GRLF1,GTF2I,GUCY2C,HLA-A,HLA-B,HNF1A,HNRNPK,HRAS,HSP90AA1,IGF1R,IKBKB,IKBKG,IL6R,INPPL1,INSR,ITGB3,JUP,KCNA5,KCNB1,KCNQ5,KDR,KHDRBS1,KIFAP3,KIT,LRP1,MAPK15,MATK,MED28,MET,MPZL1,MST1R,MUC1,MYLK,ND2,NFKBIA,NMT1,NOS2,NPHS1,NR1I2,P2RY2,PAK2,PDCD6IP,PDE6G,PDGFRB,PDPK1,PECAM1,PGR,PIK3R1,PKD1,PLCG1,PPARD,PPP2R4,PRKACA,PRKCA,PRKCD,PRKCE,PRKCH,PRKCI,PRKCZ,PRKD1,PTK2,PTK2B,PTPN1,PTPN11,PTPN18,PTPN2,PTPN21,PTPN6,PTPRA,PTPRE,PXN,RAF1,RASA1,RET,RGS16,RXRA,SH2D3C,SH3BP1,SH3PXD2A,SHB,SHC1,SKAP1,SLC9A2,SMARCB1,SMARCE1,SPTAN1,SRC,SRF,STAP2,STAT1,STAT3,STAT5A,STAT5B,STAT6,SYK,SYN1,TERT,THRA,TIAM1,TNFRSF11A,TRAF1,TRAF3,TRAF6,TRAT1,TRIP10,TRIP6,TRPC6,TRPV4,TUB,TXK,TYRO3,VCL,VIL1,WAS,WBP11,WWOX,YTHDC1,YWHAB,YWHAE,YWHAG,YWHAH,ABL1,ADRB2,ADRB3,ADRBK1,AHR,AR,ARHGAP1,ARHGAP17,ARHGAP32,ARHGAP32,ARNT,ARR3,ASAP1,ASAP2,AXL,Adrb3,BCAR1,BMX,CAV1,CAV2,CBL,CD44,CD46,CDC25C,CDC37,CDH1,CRK,CSF1R,CSK,CTNND1,DAB2,DAG1,DDR2,DOCK1,DOK1,DOK4,EFNB1,EGFR,EP300,EPHA3,EPHA4,EPHB2,EPS8,ERBB2,ESR1,ESR2,EVL,FOXO1,FYN,GAB2,GAB3,GNB2L1,GRB10,GRB2,GRIN2A,GSN,HNF1A,HSP90AA1,ITK,KHDRBS1,KIFAP3,LRP1,LYN,MAP2,MAPK8IP3,MATK,MET,MICAL1,MPZL1,MUC1,MYLK,NCOA6,ND2,PDE6G,PECAM1,PELP1,PIK3R1,PLCG1,PLD1,PLD2,PLSCR1,PRKCZ,PTK2,PTK2B,PTPN21,PTPRA,PXN,RAF1,RARA,RASA1,RET,RPL10,RPS6KB1,RPS6KB2,RXRA,SH3BP1,SHB,SKAP1,SLC9A2,SNURF,SRF,STAT1,STAT3,SYK,SYN1,THRB,TNFSF11,TRAF1,TRAF3,TRAF6,TRIP4,TRIP6,TRPC6,TRPV4,TYRO3,WAS

    Protein Size: 536

    Molekulargewicht

    60 kDa

    Gen-ID

    6714

    NCBI Accession

    NM_198291, NP_938033

    UniProt

    P12931
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