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Sperm Autoantigenic Protein 17 (SPA17) (N-Term) Peptid

SPA17 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN984303
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 21 Werktagen

Kurzübersicht für Sperm Autoantigenic Protein 17 (SPA17) (N-Term) Peptid (ABIN984303)

Target

SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFESLLEKR

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-SPA17 Antibody(ARP53719_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

    Hintergrund

    This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

    Alias Symbols: SP17, SP17-1, CT22

    Protein Interaction Partner: AKAP3,ROPN1B,AKAP3

    Protein Size: 151

    Molekulargewicht

    17 kDa

    Gen-ID

    53340

    NCBI Accession

    NM_017425, NP_059121

    UniProt

    Q15506
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