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Superoxide Dismutase 2, Mitochondrial (SOD2) (N-Term) Peptid

SOD2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN984231
  • Target Alle SOD2 Produkte
    SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-SOD2 antibody (Catalog #: ARP58529_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
    Hintergrund
    SOD2 is a member of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene encoding SOD2 have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: IPO-B, MNSOD, Mn-SOD, IPOB, MVCD6

    Protein Interaction Partner: GET4,HDHD2,NOL12,RAB4A,RPS3A,SOD2,AURKA,NOL12,RPS3A

    Protein Size: 222
    Molekulargewicht
    24 kDa
    Gen-ID
    6648
    NCBI Accession
    NM_000636, NP_000627
    UniProt
    P04179
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