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Premelanosome Protein (PMEL) Peptid

PMEL Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN983749

Kurzübersicht für Premelanosome Protein (PMEL) Peptid (ABIN983749)

Target

Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-SILV antibody (Catalog #: ARP46802_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

    Hintergrund

    SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.

    Alias Symbols: D12S53E, ME20, PMEL17, SI, SIL, gp100, P1, P100, SILV, ME20M, ME20-M

    Protein Size: 661

    Molekulargewicht

    70 kDa

    Gen-ID

    6490

    NCBI Accession

    NM_006928, NP_008859

    UniProt

    P40967
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