E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Peptid
SIAH1
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN983728
Kurzübersicht für E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Peptid (ABIN983728)
Target
SIAH1
(E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SIAH1 antibody (Catalog #: ARP34163_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) peptide
SIAH1 Reaktivität: Human, Ratte, Rind (Kuh), Hund, Maus Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
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Hintergrund
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SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Alias Symbols: SIAH1A
Protein Interaction Partner: DCC,DCC,UBE2I,UBE2I,AFF1,AFF4,APC,ATN1,BAG1,CACYBP,DAB1,DCC,EIF3J,GAPDH,HIPK3,KHDRBS3,KIF22,NUMB,PEG10,PEG3,PKD1,POU2AF1,RBBP8,SH3RF1,SIAH1,SLC9A3R2,SNCAIP,SYP,TUBA1A,TUBA1B,TUBA3C,TUBA4A,TUBA8,UBE2D1,AFF4,APC,BAG1,CACYBP,DAB1,DCC,HIF1AN,KHDRBS3,KIF22,NUMB,PEG10,PEG3,PIAS1,PIAS2,PIAS3,POU2AF1,RBBP8,SIAH1,SYP,TBL1X,TRIB3,UBE2D1,UBE2E3,UBE2I,VAV1
Protein Size: 313 -
Molekulargewicht
- 35 kDa
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Gen-ID
- 6477
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NCBI Accession
- NM_001006610, NP_001006611
Target
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