Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) Peptid
Kurzübersicht für Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) Peptid (ABIN983627)
Target
Spezies
Quelle
Applikation
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SF3B4 antibody (Catalog #: ARP40609_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
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Hintergrund
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SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Alias Symbols: Hsh49, SAP49, SF3b49
Protein Interaction Partner: SF3B2,BMPR1A,FAM115A,MAPK9,NCK2,SF3B2,SS18L1,STK19,SUMO4,TCERG1,BMPR1A,CDC5L,FAM115A,MAPK9,NCK2,RNU11,RNU12-2P,SF3A2,SF3B1,SF3B2,SMNDC1,SS18L1,TCERG1
Protein Size: 424 -
Molekulargewicht
- 47 kDa
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Gen-ID
- 10262
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NCBI Accession
- NM_005850, NP_005841
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UniProt
- Q15427
Target
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