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Splicing Factor 1 (SF1) Peptid

SF1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN983614
  • Target Alle Splicing Factor 1 (SF1) Produkte
    Splicing Factor 1 (SF1)
    Spezies
    Human
    Quelle
    • 9
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-SF1 antibody (Catalog #: ARP41213_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Splicing Factor 1 (SF1)
    Hintergrund
    SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.This gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region, this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    Alias Symbols: D11S636, ZFM1, ZNF162, BBP, MBBP

    Protein Interaction Partner: BCL2,DDX17,EWSR1,FUS,PLSCR1,PRKG1,PRPF40A,RBPMS,TAF15,TCERG1,TRIM23,U2AF2,WWP2,DDX17,EWSR1,FUS,PLSCR1,RBPMS,TAF15,TCERG1,TRIM23,U2AF2,U2AF2,WWP2

    Protein Size: 638
    Molekulargewicht
    69 kDa
    Gen-ID
    7536
    NCBI Accession
    NM_201995, NP_973724
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