Selenoprotein N, 1 (SEPN1) (C-Term) Peptid
SEPN1
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN983551
Kurzübersicht für Selenoprotein N, 1 (SEPN1) (C-Term) Peptid (ABIN983551)
Target
SEPN1
(Selenoprotein N, 1 (SEPN1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- C-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SEPN1 antibody (Catalog #: ARP47655_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SEPN1 (Selenoprotein N, 1 (SEPN1))
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Hintergrund
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SEPN1 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Mutations in SEPN1 gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: FLJ24021, MDRS1, RSMD1, RSS, SELN, CFTD
Protein Size: 590 -
Molekulargewicht
- 62 kDa
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Gen-ID
- 57190
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NCBI Accession
- NM_020451, NP_065184
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UniProt
- Q9NZV5
Target
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