Translocation Protein 1 (TLOC1) (Middle Region) Peptid
TLOC1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN983506
Kurzübersicht für Translocation Protein 1 (TLOC1) (Middle Region) Peptid (ABIN983506)
Target
SEC62 (TLOC1)
(Translocation Protein 1 (TLOC1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- KYDKDIKKEK DKGKAESGKE EDKKSKKENI KDEKTKKEKE KKKDGEKEES
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SEC62 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))
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Hintergrund
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Alias Symbols: Dtrp1, FLJ32803, HTP1, TLOC1, TP-1
Protein Interaction Partner: CIC,SEC63
Protein Size: 399 -
Molekulargewicht
- 46 kDa
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Gen-ID
- 7095
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NCBI Accession
- NM_003262, NP_003253
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UniProt
- Q99442
Target
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