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Syndecan Binding Protein (Syntenin) (SDCBP) (Middle Region) Peptid

SDCBP Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN983478
  • Target Alle SDCBP Produkte
    SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 7
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-SDCBP antibody (Catalog #: ARP44536_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
    Hintergrund
    SDCBP was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: MDA-9, ST1, SYCL, TACIP18

    Protein Interaction Partner: EFNB2,EPHA7,NF2,NRXN1,SDC3,TGFA,CADM1,CD6,EFNB1,EFNB2,EPHB2,GRIA1,GRIA2,GRIA3,GRIA4,GRIK1,GRIK2,GRM3,IL5RA,NF2,NFASC,PTPRJ,RAB5A,RNF11,SDC1,SDC2,SDC4,SDCBP,SDCBP2,SLC6A5,SOX4,STX1A,TGFA,ULK1,WDR91,EFNB1,GRIA1,GRIA2,GRIA3,GRIA4,GRIK1,GRIK2,GRIK3,GRM3,GRM7,IL5RA,NF2,PTPRJ,RAB5A,SDC1,SDC2,SOX4,TRAF6,ULK1

    Protein Size: 298
    Molekulargewicht
    32 kDa
    Gen-ID
    6386
    NCBI Accession
    NM_001007067, NP_001007068
    UniProt
    O00560
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