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Retinoid X Receptor, gamma (RXRG) Peptid

RXRG Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN983356

Kurzübersicht für Retinoid X Receptor, gamma (RXRG) Peptid (ABIN983356)

Target

Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Spezies

Human

Quelle

  • 6
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-RXRG antibody (Catalog #: ARP35815_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

    Hintergrund

    RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: RXRC, NR2B3

    Protein Interaction Partner: CAMK2B,CHGB,CREBBP,LRSAM1,MAP4,NCOA6,NCOR2,NR1H2,NR1H3,NR1H4,NR1I2,NR4A1,PNO1,PPARA,PPARD,PPARG,RARA,RARB,RARG,SRF,THRA,THRB,VDR,ITGB3BP,JUB,NR0B2,NR4A1,Nr0b2,PPARA,RARA,RPAP2,SRF

    Protein Size: 463

    Molekulargewicht

    51 kDa

    Gen-ID

    6258

    NCBI Accession

    NM_006917, NP_008848

    UniProt

    P48443
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