Runt-Related Transcription Factor 2 (RUNX2) Peptid
RUNX2
Wirt: Synthetic
BP, WB
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- Target Alle RUNX2 Produkte
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RUNX2 antibody (Catalog #: ARP36679_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- Hintergrund
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The RUNX2 gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Protein Interaction Partner: RB1,AR,AXIN1,CBFB,CCNB1,CDK1,CEBPB,DVL2,EP300,ETS1,FOS,HDAC3,HDAC4,HDAC6,JUN,LEF1,MAP3K4,MSX2,MYST4,PRKCD,RB1,SMAD2,SMAD3,SMAD6,TAF1A,UBTF,XRCC5,XRCC6,YAP1,ETS1,FOS,HDAC3,HDAC4,HDAC6,JUN,LEF1,MSX2,MYST4,SMAD1,SMAD2,SMAD3,SMAD5,STUB1,THOC4,TLE1,YAP1
Protein Size: 589 - Molekulargewicht
- 64 kDa
- Gen-ID
- 860
- UniProt
- Q5T802
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