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Ribosomal Protein L22 (RPL22) (C-Term) Peptid

RPL22 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN983184

Kurzübersicht für Ribosomal Protein L22 (RPL22) (C-Term) Peptid (ABIN983184)

Target

RPL22 (Ribosomal Protein L22 (RPL22))

Spezies

Human

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    TSEVPFSKRY LKYLTKKYLK KNNLRDWLRV VANSKESYEL RYFQINQDEE

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-RPL22 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    RPL22 (Ribosomal Protein L22 (RPL22))

    Hintergrund

    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3,21 translocations, however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2.

    Alias Symbols: EAP, HBP15, HBP15/L22, L22

    Protein Interaction Partner: CSE1L,NSFL1C,CD4,CDC42,CSE1L,NSFL1C,POU5F1,UBC

    Protein Size: 128

    Molekulargewicht

    14 kDa

    Gen-ID

    6146

    NCBI Accession

    NM_000983, NP_000974

    UniProt

    P35268
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